DDIT4L antibody (N-Term)

Catalog No. ABIN2749082

This Mouse Monoclonal antibody specifically detects DDIT4L in WB and ICFC. It exhibits reactivity toward Human.

Quick Overview for DDIT4L antibody (N-Term) (ABIN2749082)

Target: DDIT4L (DNA-Damage-Inducible Transcript 4-Like (DDIT4L))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DDIT4L antibody is un-conjugated

Application: Western Blotting (WB), Intracellular Flow Cytometry (ICFC)

Clone: DDIT-03

Product Details anti-DDIT4L Antibody

Binding Specificity: AA 2-98, N-Term

Purpose: Anti-DDIT4L Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for DDIT4L

Target: DDIT4L (DNA-Damage-Inducible Transcript 4-Like (DDIT4L))

Alternative Name: DDIT4L

Background: DNA damage inducible transcript 4 like,DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.,DDIT4L, REDD2, Rtp801L

Gene ID: 115265

UniProt: Q96D03