CLIC5 antibody (AA 160-173) (PE)

Catalog No. ABIN2749145

This Mouse Monoclonal antibody specifically detects CLIC5 in ICFC. It exhibits reactivity toward Human.

Quick Overview for CLIC5 antibody (AA 160-173) (PE) (ABIN2749145)

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CLIC5 antibody is conjugated to PE

Application: Intracellular Flow Cytometry (ICFC)

Clone: CLIC5-02

Product Details anti-CLIC5 Antibody (PE)

Binding Specificity: AA 160-173

Purpose: Anti-CLIC5 PE

Specificity: Mouse monoclonal antibody CLIC5-02 recognizes CLIC5a, a 32 kDa intracellular protein which associates with proteins of actin complexes. Crossreactivity with CLIC5b was not determined.

Cross-Reactivity (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: KLH-conjugated peptide corresponding to the amino acids 160-173 of human CLIC5a (Cys-Ile-Asp-Ala-Asn-Thr-Ser-Asp-Lys-Gly-Ser-Arg-Arg coupled with KLH).

Isotype: IgG2b kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for CLIC5

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Alternative Name: CLIC5

Background: Chloride intracellular channel 5,CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus. Human CLIC5 is transcribed in two isoforms, 32 kDa CLIC5a (251 amino acids) and 49 kDa CLIC5b (410 amino acids). These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo. CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures.,MST130, DFNB102, DFNB103, MSTP130

Gene ID: 53405

UniProt: Q9NZA1

Pathways: Sensory Perception of Sound