CLIC5 antibody (C-Term)

Catalog No. ABIN2776220

There is 1 publication for this product available. The Rabbit Polyclonal anti-CLIC5 antibody is suitable to detect CLIC5 in samples from Human, Rat, Mouse, Guinea Pig, Horse, Rabbit, Cow, Dog and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for CLIC5 antibody (C-Term) (ABIN2776220)

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Rabbit, Cow, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CLIC5 Antibody

Binding Specificity: C-Term

Purpose: CLIC5 Antibody - C-terminal region

Sequence: YRNYDIPAEM TGLWRYLKNA YARDEFTNTC AADSEIELAY ADVAKRLSRS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against CLIon Channel5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLIC5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096933

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CLIC5 antibody (ABIN2776220)

Tavasoli, Al-Momany, Wang, Li, Edwards, Ballermann: "Both CLIC4 and CLIC5A activate ERM proteins in glomerular endothelium." in: American journal of physiology. Renal physiology, Vol. 311, Issue 5, pp. F945-F957, (2016) (PubMed).

Target Details for CLIC5

Target: CLIC5 (Chloride Intracellular Channel 5 (CLIC5))

Alternative Name: CLIC5

Background:

Background Information: Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIon Channel5 specifically associates with the cytoskeleton of placenta microvilli.Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIon Channel5 specifically associates with the cytoskeleton of placenta microvilli.[supplied by OMIM].

Gene Name: Chloride intracellular channel 5

Alternative Symbols: MST130, DFNB102, DFNB103, MSTP130

Protein Name: Chloride intracellular channel protein 5

Molecular Weight: 28kDa

Gene ID: 53405

NCBI Accession: NP_058625

UniProt: Q9NZA1

Pathways: Sensory Perception of Sound