DDIT4L antibody (AA 2-98) (PE)

Catalog No. ABIN2749146

The Mouse Monoclonal anti-DDIT4L antibody has been validated for ICFC. It is suitable to detect DDIT4L in samples from Human.

Quick Overview for DDIT4L antibody (AA 2-98) (PE) (ABIN2749146)

Target: DDIT4L (DNA-Damage-Inducible Transcript 4-Like (DDIT4L))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DDIT4L antibody is conjugated to PE

Application: Intracellular Flow Cytometry (ICFC)

Clone: DDIT-03

Product Details anti-DDIT4L Antibody (PE)

Binding Specificity: AA 2-98

Purpose: Anti-DDIT4L PE

Specificity: The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.

Cross-Reactivity (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for DDIT4L

Target: DDIT4L (DNA-Damage-Inducible Transcript 4-Like (DDIT4L))

Alternative Name: DDIT4L

Background: DNA damage inducible transcript 4 like,DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.,DDIT4L, REDD2, Rtp801L

Gene ID: 115265

UniProt: Q96D03