OPAL1 antibody (AA 152-342) (PE)
Quick Overview for OPAL1 antibody (AA 152-342) (PE) (ABIN2749162)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 152-342
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Purpose
- Anti-OPAL1 PE
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Cross-Reactivity (Details)
- Human
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Characteristics
- The mouse monoclonal antibody OPAL1-01 recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megacaryocytes and platelets.
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Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogen
- Recombinant fragment of human OPAL1 (amino acids 152-342)
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Isotype
- IgG2a
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Application Notes
- Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze,Protect from prolonged exposure to light
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- OPAL1 (WBP1L) (WW Domain Binding Protein 1 Like (WBP1L))
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Alternative Name
- OPAL1
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Background
- WW domain binding protein 1 like,OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.,WBP1L
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Gene ID
- 54838
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UniProt
- Q9NX94
Target
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