JNK antibody (pThr183, pTyr185)

Catalog No. ABIN7302256

The Rabbit Polyclonal anti-JNK antibody is suitable to detect JNK in samples from Human, Mouse, Rat and Chicken. It has been validated for WB and IF.

Quick Overview for JNK antibody (pThr183, pTyr185) (ABIN7302256)

Target: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JNK antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-JNK Antibody

Binding Specificity: pThr183, pTyr185

Purpose: Rabbit polyclonal antibody to JNK1/2/3 (Phospho-T183/Y185)

Specificity: Recognizes endogenous levels of JNK1/2/3 protein only when phosphorylated at T183/Y185.

Characteristics: Rabbit polyclonal antibody to JNK1/2/3 (pT183/Y185)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T183/Y185 of human JNK1/2/3 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IF/IC (1/50 - 1/200)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for JNK

Target: JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

Alternative Name: JNK1/2/3

Background: MAPK8, JNK1, PRKM8, SAPK1, SAPK1C, Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, JNK-46, Stress-activated protein kinase 1c, SAPK1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, MAPK9, JNK2, PRKM9, SAPK1A, Mitogen-activated protein kinase 9, MAP kinase 9, MAPK 9, JNK-55, Stress-activated protein kinase 1a, SAPK1a, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2, MAPK10, JNK3, JNK3A, PRKM10, SAPK1B, Mitogen-activated protein kinase 10, MAP kinase 10, MAPK 10, MAP kinase p49 3F12, Stress-activated protein kinase 1b, SAPK1b, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3

Gene ID: 5599, 26419, 116554

UniProt: P45983

Pathways: MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins