OS9 antibody (C-Term)

Catalog No. ABIN2773850

Product Details anti-OS9 Antibody

Target: OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OS9 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LKEIFFNILV PGAEEAQKER QRQKELESNY RRVWGSPGGE GTGDLDEFDF

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against OS9. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human OS9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OS9

Target: OS9 (Osteosarcoma Amplified 9, Endoplasmic Reticulum Lectin (OS9))

Alternative Name: OS9 (OS9 Products)

Synonyms: OS-9 antibody, zgc:153838 antibody, 4632413K17Rik antibody, AU022351 antibody, Os-9 antibody, ERLEC2 antibody, OS9, endoplasmic reticulum lectin antibody, osteosarcoma amplified 9, endoplasmic reticulum lectin antibody, amplified in osteosarcoma antibody, OS9 antibody, os9 antibody, Os9 antibody

Background: This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: ERLEC2, OS-9
Protein Interaction Partner: SYVN1, SEL1L, UBC, DCSTAMP, SERPINI1, FBXO6, EGFR, DERL2, CLN5, SNRPD2, SMAD2, FOXM1, ACVR1B, ZNF512B, env, CREB3, RBX1, UBE2J1, CERCAM, NUP210, OS9, HYOU1, VCP, HSP90B1, PPIB, PLOD2, HSPA5, SERPINH1, BSG, FOXRED2, COLGALT1, UGGT2, DNAJB11, ERLEC1, HIF1A,
Protein Size: 667

Molecular Weight: 73 kDa

Gene ID: 10956

NCBI Accession: NM_006812, NP_006803

UniProt: Q13438

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome