Adenylate Kinase 1 antibody (Middle Region)
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- Target See all Adenylate Kinase 1 (AK1) Antibodies
- Adenylate Kinase 1 (AK1)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Dog, Sheep, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Adenylate Kinase 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RIGQPTLLLY VDAGPETMTQ RLLKRGETSG RVDDNEETIK KRLETYYKAT
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 86%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against AK1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human AK1
- Top Product
- Discover our top product AK1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 194 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Adenylate Kinase 1 (AK1)
- Alternative Name
- AK1 (AK1 Products)
- Synonyms
- ADK-1 antibody, AK1 antibody, CG17146 antibody, DAK1 antibody, Dak1 antibody, Dmel\\CG17146 antibody, adk1 antibody, bs34e10.y1 antibody, ak5 antibody, ADENYLATE KINASE 1 antibody, MLE2.3 antibody, MLE2_3 antibody, adenylate kinase 1 antibody, Ak-1 antibody, B430205N08Rik antibody, Ak 1 antibody, zgc:91930 antibody, Myokinase antibody, Adenylate kinase 1 antibody, adenylate kinase 1 antibody, Adk1 antibody, ak1 antibody, AK1 antibody, ADK1 antibody, Ak1 antibody
- Background
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Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, IDH1, APP, TERF2IP, TINF2, TERF1, TRIM63, FHL2, KMT2C,
Protein Size: 194 - Molecular Weight
- 22 kDa
- Gene ID
- 203
- NCBI Accession
- NM_000476, NP_000467
- UniProt
- P00568
- Pathways
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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