COX7B antibody (N-Term)

Catalog No. ABIN2773999

This Rabbit Polyclonal antibody specifically detects COX7B in WB. It exhibits reactivity toward Human, Rat, Mouse, Pig and Rabbit.

Quick Overview for COX7B antibody (N-Term) (ABIN2773999)

Target: COX7B (Cytochrome C Oxidase Subunit VIIb (COX7B))

Reactivity: Human, Rat, Mouse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX7B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COX7B Antibody

Binding Specificity: N-Term

Purpose: COX7B Antibody - N-terminal region

Sequence: MFPLVKSALN RLQVRSIQQT MARQSHQKRT PDFHDKYGNA VLASGATFCI

Predicted Reactivity: Human: 100%, Mouse: 92%, Pig: 77%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against COX7B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COX7B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51975-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for COX7B

Target: COX7B (Cytochrome C Oxidase Subunit VIIb (COX7B))

Alternative Name: COX7B

Background:

Targeted Subunit: 7B, mitochondrial

Background Information: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22, respectively.

Gene Name: Cytochrome c oxidase subunit VIIb

Alternative Symbols: APLCC, LSDMCA2

Protein Name: Cytochrome c oxidase subunit 7B, mitochondrial

Molecular Weight: 6kDa

Gene ID: 1349

NCBI Accession: NP_001857

UniProt: P24311

Pathways: Proton Transport