Ubiquilin 2 antibody (N-Term)

Catalog No. ABIN2774254

The Rabbit Polyclonal anti-Ubiquilin 2 antibody is suitable to detect Ubiquilin 2 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for Ubiquilin 2 antibody (N-Term) (ABIN2774254)

Target: Ubiquilin 2 (UBQLN2)

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ubiquilin 2 Antibody

Binding Specificity: N-Term

Purpose: UBQLN2 Antibody - N-terminal region

Sequence: LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTQPSNAAG TNTTSASTPR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 87%, Rabbit: 87%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against UBQLN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBQLN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59353-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ubiquilin 2

Target: Ubiquilin 2 (UBQLN2)

Alternative Name: UBQLN2

Background:

Background Information: This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.

Gene Name: Ubiquilin 2

Alternative Symbols: DSK2, ALS15, CHAP1, N4BP4, PLIC2, HRIHFB2157

Protein Name: Ubiquilin-2

Molecular Weight: 66kDa

Gene ID: 29978

NCBI Accession: NP_038472

UniProt: Q9UHD9