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FDPS antibody (C-Term)

This anti-FDPS antibody is a Rabbit Polyclonal antibody detecting FDPS in WB and IHC. Suitable for Human, Rat, Mouse, Dog, Horse, Pig, Rabbit, Cow and Guinea Pig.
Catalog No. ABIN2774296

Quick Overview for FDPS antibody (C-Term) (ABIN2774296)

Target

See all FDPS Antibodies
FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reactivity

Human, Rat, Mouse, Dog, Horse, Pig, Rabbit, Cow, Guinea Pig

Host

  • 49
  • 10
Rabbit

Clonality

  • 47
  • 12
Polyclonal

Conjugate

  • 38
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FDPS antibody is un-conjugated

Application

  • 43
  • 27
  • 21
  • 13
  • 8
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Binding Specificity

    • 11
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequence

    VKYKTAFYSF YLPIAAAMYM AGIDGEKEHA NAKKILLEMG EFFQIQDDYL

    Predicted Reactivity

    Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

    Characteristics

    This is a rabbit polyclonal antibody against FDPS. It was validated on Western Blot.

    Purification

    Affinity Purified
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 353 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    FDPS (Farnesyl Diphosphate Synthase (FDPS))

    Alternative Name

    FDPS

    Background

    This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: FPPS, FPS
    Protein Interaction Partner: UBC, SUMO2, NME1, IDH1, ADSS, NME1-NME2, STAMBP, TALDO1, SORD, PLS3, EGFR, EIF4ENIF1, ATXN1, FGFR1,
    Protein Size: 353

    Molecular Weight

    38 kDa

    Gene ID

    2224

    NCBI Accession

    NM_001135822, NP_001129294

    UniProt

    P14324

    Pathways

    Regulation of Muscle Cell Differentiation
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