BAG5 antibody (N-Term)

Catalog No. ABIN2774330

This Rabbit Polyclonal antibody specifically detects BAG5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse and Guinea Pig.

Quick Overview for BAG5 antibody (N-Term) (ABIN2774330)

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAG5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BAG5 Antibody

Binding Specificity: N-Term

Purpose: BAG5 Antibody - N-terminal region

Sequence: LSDDKNYKKL ERILTKQLFE IDSVDTEGKG DIQQARKRAA QETERLLKEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BAG5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61997-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BAG5

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Alternative Name: BAG5

Background:

Background Information: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.

Gene Name: BCL2-associated athanogene 5

Alternative Symbols: BAG-5

Protein Name: BAG family molecular chaperone regulator 5

Molecular Weight: 56kDa

Gene ID: 9529

NCBI Accession: NP_001015049

UniProt: Q9UL15

Pathways: SARS-CoV-2 Protein Interactome