MRPL43 antibody (C-Term)

Catalog No. ABIN2774349

Product Details anti-MRPL43 Antibody

Target: MRPL43 (Mitochondrial Ribosomal Protein L43 (MRPL43))

Binding Specificity: C-Term

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL43 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WHPFTNKPTT FRGLRPREVQ DPAPAQDTGL RLSAVAPQIL LPGWPDPPDL

Predicted Reactivity: Human: 100%, Pig: 100%

Characteristics: This is a rabbit polyclonal antibody against MRPL43. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 215 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL43

Target: MRPL43 (Mitochondrial Ribosomal Protein L43 (MRPL43))

Alternative Name: MRPL43 (MRPL43 Products)

Synonyms: bMRP36a antibody, 4930442D21Rik antibody, mitochondrial ribosomal protein L43 antibody, MRPL43 antibody, Mrpl43 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions.
Alias Symbols: MGC17989, MGC48892, bMRP36a
Protein Interaction Partner: FXR2, MDM2, SRPK1, NPM1, VCAM1, ITGA4, RPS18, NDUFA2, MRPL40, MRPL47, LAMTOR3, CAND1, COPS5, UBC, Ybx1, ICT1, DDX56, ARRB2,
Protein Size: 215

Molecular Weight: 23 kDa

Gene ID: 84545

NCBI Accession: NM_176792, NP_789762

UniProt: Q8N983