MRPL43 antibody (N-Term)

Catalog No. ABIN2789213

The Rabbit Polyclonal anti-MRPL43 antibody (ABIN2789213) specifically detects MRPL43 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig and Horse samples.

Quick Overview for MRPL43 antibody (N-Term) (ABIN2789213)

Target: MRPL43 (Mitochondrial Ribosomal Protein L43 (MRPL43))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL43 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL43 Antibody

Binding Specificity: N-Term

Purpose: MRPL43 Antibody - N-terminal region

Sequence: PSRFLASVLH NGLGRYVQQL QRLSFSVSRD GASSRGAREF VEREVIDFAR

Predicted Reactivity: Cow: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against MRPL43. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62689-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL43

Target: MRPL43 (Mitochondrial Ribosomal Protein L43 (MRPL43))

Alternative Name: MRPL43

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions.

Gene Name: Mitochondrial ribosomal protein L43

Alternative Symbols: L43mt, MRP-L43, bMRP36a

Protein Name: 39S ribosomal protein L43, mitochondrial

Molecular Weight: 23kDa

Gene ID: 84545

NCBI Accession: NP_789762

UniProt: Q8N983