MUSK antibody (N-Term)

Catalog No. ABIN2774361

The Rabbit Polyclonal anti-MUSK antibody is suitable to detect MUSK in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for MUSK antibody (N-Term) (ABIN2774361)

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUSK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MUSK Antibody

Binding Specificity: N-Term

Sequence: ENSRIAVLES GSLRIHNVQK EDAGQYRCVA KNSLGTAYSK VVKLEVEVFA

Predicted Reactivity: Cow: 93%, Dog: 83%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against MUSK. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 773 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MUSK

Target: MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))

Alternative Name: MUSK

Background: This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.
Alias Symbols: MGC126323, MGC126324
Protein Interaction Partner: HSP90AA1, NEDD8, PDZRN3, UBC, SYNE1, DOK7, COLQ, RAPSN,
Protein Size: 773

Molecular Weight: 85 kDa

Gene ID: 4593

NCBI Accession: NM_001166281, NP_001159753

Pathways: RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development