PDIA3 antibody (C-Term)
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- Target See all PDIA3 Antibodies
- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit, Horse, Sheep, Goat, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDIA3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Sequence
- YFSPANKKLN PKKYEGGREL SDFISYLQRE ATNPPVIQEE KPKKKKKAQE
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against PDIA3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PDIA3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 505 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
- Alternative Name
- PDIA3 (PDIA3 Products)
- Synonyms
- ER60 antibody, ERp57 antibody, ERp60 antibody, ERp61 antibody, GRP57 antibody, GRP58 antibody, HsT17083 antibody, P58 antibody, PI-PLC antibody, grp-58 antibody, 58kDa antibody, Erp antibody, Grp58 antibody, PDI antibody, PDI-Q2 antibody, PLC[a] antibody, Plca antibody, 1 antibody, 25D3-membrane-associated antibody, sb:cb825 antibody, erp57 antibody, grp58 antibody, pdia3 antibody, protein disulfide isomerase family A member 3 antibody, protein disulfide-isomerase A3 antibody, protein disulfide isomerase associated 3 antibody, protein disulfide isomerase family A, member 3 antibody, protein disulfide isomerase family A member 3 S homeolog antibody, PDIA3 antibody, Tsp_10062 antibody, Pdia3 antibody, pdia3 antibody, pdia3.S antibody
- Background
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This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Alias Symbols: ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC
Protein Interaction Partner: FUS, UBC, MDM2, SUZ12, ABCE1, RBBP4, RAB1A, PGD, MTAP, MTPN, BCCIP, CNDP2, NANS, DAK, ACOT7, NPEPPS, SLC9A3R1, RPL23, SMS, LDHA, HSPD1, CSE1L, ATP6V1A, ADSS, EGFR, UBD, CANX, CALR, HDAC10, MTOR, EFEMP1, ATF2, COL6A1, CLU, APP, ADAM10, AGRN, DCBLD1, RICTOR
Protein Size: 505 - Molecular Weight
- 56 kDa
- Gene ID
- 2923
- NCBI Accession
- NM_005313, NP_005304
- UniProt
- P30101
- Pathways
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
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