RAP2A antibody (N-Term)

Catalog No. ABIN2774388

The Rabbit Polyclonal anti-RAP2A antibody is suitable to detect RAP2A in samples from Mouse, Human, Rat, Dog, Horse, Cow, Zebrafish (Danio rerio), Sheep, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for RAP2A antibody (N-Term) (ABIN2774388)

Target: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Reactivity: Mouse, Human, Rat, Dog, Horse, Cow, Zebrafish (Danio rerio), Sheep, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAP2A Antibody

Binding Specificity: N-Term

Purpose: RAP2A Antibody - N-terminal region

Sequence: KYDPTIEDFY RKEIEVDSSP SVLEILDTAG TEQFASMRDL YIKNGQGFIL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RAP2A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64033-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAP2A

Target: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Alternative Name: RAP2A

Background:

Background Information: RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

Gene Name: RAP2A, member of RAS oncogene family

Alternative Symbols: KREV, RAP2, K-REV, RbBP-30

Protein Name: Ras-related protein Rap-2a

Molecular Weight: 20kDa

Gene ID: 5911

NCBI Accession: NP_066361

UniProt: P10114