RAP2A antibody

Catalog No. ABIN7465115

Product Details anti-RAP2A Antibody

Target: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP2A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human RAP2A Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RAP2A

Target: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Alternative Name: RAP2A, member of RAS oncogene family (RAP2A Products)

Synonyms: krev antibody, rap2 antibody, k-rev antibody, rbbp-30 antibody, RAP2A antibody, K-REV antibody, KREV antibody, RAP2 antibody, RbBP-30 antibody, 5830461H18Rik antibody, RAP2A, member of RAS oncogene family antibody, Rap2A GTPase antibody, RAP2B, member of RAS oncogene family antibody, RAS related protein 2a antibody, RAP2A antibody, Rap2a antibody, rap2a antibody, RAP2B antibody

Background: RAP2A, member of RAS oncogene family , K-REV , KREV , RAP2 , RbBP-30,Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

Molecular Weight: 21 kDa

Gene ID: 5911

UniProt: P10114