SEC62 antibody (Middle Region)

Catalog No. ABIN2774392

The Rabbit Polyclonal anti-SEC62 antibody (ABIN2774392) specifically detects SEC62 in WB. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse and Rabbit samples.

Quick Overview for SEC62 antibody (Middle Region) (ABIN2774392)

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC62 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SEC62 Antibody

Binding Specificity: Middle Region

Purpose: SEC62 Antibody - middle region

Sequence: KYDKDIKKEK DKGKAESGKE EDKKSKKENI KDEKTKKEKE KKKDGEKEES

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SEC62. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64182-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Alternative Name: SEC62

Background:

Background Information: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Gene Name: SEC62 homolog (S. cerevisiae)

Alternative Symbols: HTP1, TP-1, Dtrp1, TLOC1

Protein Name: Translocation protein SEC62

Molecular Weight: 46kDa

Gene ID: 7095

NCBI Accession: NP_003253

UniProt: Q99442