NEFM antibody (C-Term)

Catalog No. ABIN2774450

This anti-NEFM antibody is a Rabbit Polyclonal antibody detecting NEFM in WB. Suitable for Human, Rat, Rabbit, Cow, Dog, Horse and Sheep.

Quick Overview for NEFM antibody (C-Term) (ABIN2774450)

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reactivity: Human, Rat, Rabbit, Cow, Dog, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEFM Antibody

Binding Specificity: C-Term

Sequence: EVEGKEEVEQ ETKEKGSGRE EEKGVVTNGL DLSPADEKKG GDKSEEKVVV

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against NEFM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NEFM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 540 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Alternative Name: NEFM

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: NEF3, NF-M, NFM
Protein Interaction Partner: SART3, PARK2, RB1, SMAD2, FOS, IQCB1, SIRT7, UBC, DISC1, TNIK, SQSTM1, MINK1, STXBP1, NEFH, APOE,
Protein Size: 540

Molecular Weight: 59 kDa

Gene ID: 4741

NCBI Accession: NM_001105541, NP_001099011

UniProt: E9PBF7

Pathways: Brown Fat Cell Differentiation