MRPS18C antibody (N-Term)

Catalog No. ABIN2774558

The Rabbit Polyclonal anti-MRPS18C antibody (ABIN2774558) specifically detects MRPS18C in WB. The antibody is reactive with Human and Rat samples.

Quick Overview for MRPS18C antibody (N-Term) (ABIN2774558)

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS18C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPS18C Antibody

Binding Specificity: N-Term

Purpose: MRPS18C Antibody - N-terminal region

Sequence: GTHTVLWRRG CSQQVSSNED LPISMENPYK EPLKKCILCG KHVDYKNVQL

Predicted Reactivity: Human: 100%, Rat: 75%

Characteristics: This is a rabbit polyclonal antibody against MRPS18C. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MRPS18C

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70894-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPS18C

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Alternative Name: MRPS18C

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins.

Alternative Symbols: CGI-134, S18mt-c, MRPS18-1, mrps18-c, MRP-S18-1, MRP-S18-c

Molecular Weight: 15kDa

Gene ID: 51023

NCBI Accession: NP_057151

UniProt: Q9Y3D5