Retinoid X Receptor beta antibody (N-Term)

Catalog No. ABIN2774660

Product Details anti-Retinoid X Receptor beta Antibody

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoid X Receptor beta antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GDSGRDSRSP DSSSPNPLPQ GVPPPSPPGP PLPPSTAPSL GGSGAPPPPP

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RXRB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RXRB

Application Details

Application Notes: WB Suggested Anti-RXRB Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 533 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Alternative Name: RXR-beta / RXRB (RXRB Products)

Synonyms: DAUDI6 antibody, H-2RIIBP antibody, NR2B2 antibody, RCoR-1 antibody, RXR-beta antibody, RXRbeta antibody, rxrb antibody, RXRB antibody, nr2b2 antibody, daudi6 antibody, rcor-1 antibody, h-2riibp antibody, NR2B2-A antibody, RXR antibody, RXRA antibody, etID309733.19 antibody, rxre antibody, wu:fb93c09 antibody, AL023085 antibody, Nr2b2 antibody, Rub antibody, rxrd antibody, unp286 antibody, retinoid X receptor beta antibody, retinoid X receptor beta S homeolog antibody, retinoid x receptor, beta a antibody, retinoid x receptor, beta b antibody, RXRB antibody, Rxrb antibody, rxrb.S antibody, rxrb antibody, rxrba antibody, rxrbb antibody

Background: RXRB is a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DAUDI6, H-2RIIBP, MGC1831, NR2B2, RCoR-1
Protein Interaction Partner: NR1H3, RARB, UBC, PTMS, CACNA1B, SPOP, RARA, ZDHHC12, VDR, GRIP1, SRA1, MED1, Cebpb, SUMO2, NR1I2, NR1H2, NR2C2, THRB, SRC, RARG, PPARG, PPARD, NR4A2, MAP4, GTF2H1, NR3C1, TAF11, THRA, TACC2, AKAP13, NR0B2, NR2E3, NCOA1, NRIP1, NCOA3, RXRB,
Protein Size: 533

Molecular Weight: 57 kDa

Gene ID: 6257

NCBI Accession: NM_021976, NP_068811

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway