YY1 antibody (Middle Region)

Catalog No. ABIN2774666

The Rabbit Polyclonal anti-YY1 antibody (ABIN2774666) specifically detects YY1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow and Zebrafish (Danio rerio) samples.

Quick Overview for YY1 antibody (Middle Region) (ABIN2774666)

Target: YY1 (YY1 Transcription Factor (YY1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YY1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-YY1 Antibody

Binding Specificity: Middle Region

Purpose: YY1 Antibody - middle region

Sequence: KQLAEFARMK PRKIKEDDAP RTIACPHKGC TKMFRDNSAM RKHLHTHGPR

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against YY1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human YY1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for YY1

Target: YY1 (YY1 Transcription Factor (YY1))

Alternative Name: YY1

Background:

Background Information: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

Gene Name: YY1 transcription factor

Alternative Symbols: DELTA, NF-E1, UCRBP, GADEVS, INO80S, YIN-YANG-1

Protein Name: Transcriptional repressor protein YY1

Molecular Weight: 45kDa

Gene ID: 7528

NCBI Accession: NP_003394

UniProt: P25490