FBXL7 antibody (N-Term)

Catalog No. ABIN2774703

The Rabbit Polyclonal anti-FBXL7 antibody (ABIN2774703) specifically detects FBXL7 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Cow, Horse and Rabbit samples.

Quick Overview for FBXL7 antibody (N-Term) (ABIN2774703)

Target: FBXL7 (F-Box and Leucine-Rich Repeat Protein 7 (FBXL7))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FBXL7 Antibody

Binding Specificity: N-Term

Purpose: FBXL7 Antibody - N-terminal region

Sequence: IRLASRPQKE QASIDRLPDH SMVQIFSFLP TNQLCRCARV CRRWYNLAWD

Predicted Reactivity: Cow: 92%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXL7. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100138

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXL7

Target: FBXL7 (F-Box and Leucine-Rich Repeat Protein 7 (FBXL7))

Alternative Name: FBXL7

Background:

Background Information: FBXL7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.

Gene Name: F-box and leucine-rich repeat protein 7

Alternative Symbols: FBL6, FBL7

Protein Name: F-box/LRR-repeat protein 7

Molecular Weight: 54kDa

Gene ID: 23194

NCBI Accession: NP_036436

UniProt: Q9UJT9