SNRNP200 antibody (N-Term)

Catalog No. ABIN2775221

The Rabbit Polyclonal anti-SNRNP200 antibody (ABIN2775221) specifically detects SNRNP200 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Horse, Rabbit, Zebrafish (Danio rerio) and Guinea Pig samples.

Quick Overview for SNRNP200 antibody (N-Term) (ABIN2775221)

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRNP200 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNRNP200 Antibody

Binding Specificity: N-Term

Purpose: SNRNP200 Antibody - N-terminal region

Sequence: GDEDVYGEVR EEASDDDMEG DEAVVRCTLS ANLVASGELM SSKKKDLHPR

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SNRNP200. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36414-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNRNP200

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Alternative Name: SNRNP200

Background:

Background Information: Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa.

Gene Name: Small nuclear ribonucleoprotein 200 kDa (U5)

Alternative Symbols: BRR2, RP33, HELIC2, ASCC3L1, U5-200KD

Protein Name: U5 small nuclear ribonucleoprotein 200 kDa helicase

Molecular Weight: 244kDa

Gene ID: 23020

NCBI Accession: NP_054733

UniProt: O75643

Pathways: Ribonucleoprotein Complex Subunit Organization