SNRNP200 antibody (AA 400-450)

Catalog No. ABIN7454918

Product Details anti-SNRNP200 Antibody

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Binding Specificity: AA 400-450

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRNP200 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-SNRNP200 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SNRNP200

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Alternative Name: SNRNP200 (SNRNP200 Products)

Synonyms: ASCC3L1 antibody, BRR2 antibody, HELIC2 antibody, RP33 antibody, U5-200KD antibody, small nuclear ribonucleoprotein U5 subunit 200 antibody, SNRNP200 antibody

Background: Background: U5 small nuclear ribonucleoprotien 200 kDa (SNRNP200) is one of nine U5 snRNP-specific proteins. SNRNP200 belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in the SNRNP200 gene cause autosomal-dominant retinitis pigmentosa [taken from NCBI Entrez Gene (Gene ID: 23020)].

Gene ID: 23020

NCBI Accession: NP_054733

UniProt: O75643

Pathways: Ribonucleoprotein Complex Subunit Organization