Fibrinogen beta Chain antibody (Middle Region)

Catalog No. ABIN2775299

Product Details anti-Fibrinogen beta Chain Antibody

Target: Fibrinogen beta Chain (FGB)

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrinogen beta Chain antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GNDKISQLTR MGPTELLIEM EDWKGDKVKA HYGGFTVQNE ANKYQISVNK

Predicted Reactivity: Cow: 91%, Dog: 86%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FGB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FGB

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Alternative Name: FGB (FGB Products)

Synonyms: FGB antibody, 2510049G14Rik antibody, DKFZp470D0312 antibody, LOC100223598 antibody, fibrinogen antibody, Ab1-216 antibody, Ac1-581 antibody, wu:fa55c11 antibody, zgc:77116 antibody, fgb antibody, fibrinogen beta chain antibody, fibrinogen beta chain L homeolog antibody, FGB antibody, Fgb antibody, fgb antibody, fgb.L antibody

Background: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HEL-S-78p
Protein Size: 272

Molecular Weight: 29 kDa

Gene ID: 2244

NCBI Accession: NM_001184741, NP_001171670

UniProt: P02675