FADS1 antibody (N-Term)

Catalog No. ABIN2775386

This Rabbit Polyclonal antibody specifically detects FADS1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit and Guinea Pig.

Quick Overview for FADS1 antibody (N-Term) (ABIN2775386)

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FADS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FADS1 Antibody

Binding Specificity: N-Term

Purpose: FADS1 Antibody - N-terminal region

Sequence: RHPGGSRVIS HYAGQDATDP FVAFHINKGL VKKYMNSLLI GELSPEQPSF

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 83%, Horse: 83%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 83%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FADS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FADS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42383-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FADS1

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Alternative Name: FADS1

Background:

Background Information: FADS1 is a member of the fatty acid desaturase (FADS) family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1, this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Fatty acid desaturase 1

Alternative Symbols: D5D, TU12, FADS6, FADSD5, LLCDL1

Protein Name: Fatty acid desaturase 1

Molecular Weight: 52kDa

Gene ID: 3992

NCBI Accession: NP_037534

UniProt: O60427

Pathways: Regulation of Lipid Metabolism by PPARalpha