ABHD5 antibody (N-Term)

Catalog No. ABIN2775424

Product Details anti-ABHD5 Antibody

Target: ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABHD5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NRPVYAFDLL GFGRSSRPRF DSDAEEVENQ FVESIEEWRC ALGLDKMILL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against ABHD5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ABHD5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABHD5

Target: ABHD5 (Abhydrolase Domain Containing 5 (ABHD5))

Alternative Name: ABHD5 (ABHD5 Products)

Synonyms: ABHD5 antibody, cds antibody, cgi58 antibody, iecn2 antibody, ncie2 antibody, abhd5 antibody, CDS antibody, CGI58 antibody, IECN2 antibody, NCIE2 antibody, 1300003D03Rik antibody, 2010002J10Rik antibody, CGI-58 antibody, IECN5 antibody, abhydrolase domain containing 5 antibody, abhydrolase domain containing 5a antibody, abhydrolase domain containing 5 L homeolog antibody, ABHD5 antibody, abhd5 antibody, abhd5a antibody, Abhd5 antibody, abhd5.L antibody

Background: ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in ABHD5 gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.
Alias Symbols: CDS, CGI58, IECN2, MGC8731, NCIE2
Protein Interaction Partner: PNPLA2, PLIN1, Dlg4, UBC, PLIN2,
Protein Size: 349

Molecular Weight: 39 kDa

Gene ID: 51099

NCBI Accession: NM_016006, NP_057090

UniProt: Q8WTS1

Pathways: Lipid Metabolism