SLC38A4 antibody (Middle Region)

Catalog No. ABIN2775452

The Rabbit Polyclonal anti-SLC38A4 antibody is suitable to detect SLC38A4 in samples from Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Pig and Rabbit. It has been validated for WB and IHC.

Quick Overview for SLC38A4 antibody (Middle Region) (ABIN2775452)

Target: SLC38A4 (Solute Carrier Family 38 Member 4 (SLC38A4))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC38A4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SLC38A4 Antibody

Binding Specificity: Middle Region

Purpose: SLC38A4 Antibody - middle region

Sequence: LAALFGYLTF YGEVEDELLH AYSKVYTLDI PLLMVRLAVL VAVTLTVPIV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against SLC38A4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC38A4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112304

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC38A4

Target: SLC38A4 (Solute Carrier Family 38 Member 4 (SLC38A4))

Alternative Name: SLC38A4

Background:

Background Information: SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: Solute carrier family 38, member 4

Alternative Symbols: ATA3, NAT3, PAAT, SNAT4

Protein Name: Sodium-coupled neutral amino acid transporter 4

Molecular Weight: 61 kDa

Gene ID: 55089

NCBI Accession: NP_060488

UniProt: Q969I6