Connexin 31 antibody (N-Term)

Catalog No. ABIN2775592

This Rabbit Polyclonal antibody specifically detects Connexin 31 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Horse, Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Connexin 31 antibody (N-Term) (ABIN2775592)

Target: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Connexin 31 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Connexin 31 Antibody

Binding Specificity: N-Term

Purpose: Gjb3 Antibody - N-terminal region

Sequence: MDWKKLQDLL SGVNQYSTAF GRIWLSVVFV FRVLVYVVAA ERVWGDEQKD

Predicted Reactivity: Cow: 79%, Dog: 83%, Horse: 83%, Human: 83%, Mouse: 100%, Pig: 83%, Rabbit: 79%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Gjb3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42822-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Connexin 31

Target: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Alternative Name: Gjb3

Background:

Background Information: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Gene Name: Gap junction protein, beta 3

Alternative Symbols: Cnx3, Cx31, Cxnc, Cnx31, Gjb-3, D4Wsu144, D4Wsu144e

Protein Name: Gap junction beta-3 protein

Molecular Weight: 31kDa

Gene ID: 14620

NCBI Accession: NP_032152

UniProt: P28231

Pathways: Sensory Perception of Sound