Tricellulin antibody (Middle Region)

Catalog No. ABIN2775617

This Rabbit Polyclonal antibody specifically detects Tricellulin in WB. It exhibits reactivity toward Human, Rat, Mouse, Pig, Cow, Dog, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Tricellulin antibody (Middle Region) (ABIN2775617)

Target: Tricellulin (MARVELD2)

Reactivity: Human, Rat, Mouse, Pig, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tricellulin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tricellulin Antibody

Binding Specificity: Middle Region

Purpose: MARVELD2 Antibody - middle region

Sequence: PKTPFVLVVA GLAWITTIII LVLGMSMYYR TILLDSNWWP LTEFGINVAL

Predicted Reactivity: Cow: 100%, Dog: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MARVELD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MARVELD2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42885-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tricellulin

Target: Tricellulin (MARVELD2)

Alternative Name: MARVELD2

Background:

Background Information: Tight junctions (TJ) prevent leakage of solutes through the paracellular pathway of epithelial cells. MARVELD2, or tricellulin (TRIC), is an integral membrane protein concentrated at the vertically oriented TJ strands of tricellular contacts (Ikenouchi et

Gene Name: MARVEL domain containing 2

Alternative Symbols: Tric, DFNB49, MARVD2, MRVLDC2

Protein Name: MARVEL domain-containing protein 2 Ensembl ENSP00000398922 Ensembl ENSP00000414776

Molecular Weight: 52kDa

Gene ID: 153562

NCBI Accession: NP_653325

UniProt: C9J8H4

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization