CoREST antibody (Middle Region)

Catalog No. ABIN2775735

The Rabbit Polyclonal anti-CoREST antibody (ABIN2775735) specifically detects CoREST in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Cow and Horse samples.

Quick Overview for CoREST antibody (Middle Region) (ABIN2775735)

Target: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CoREST antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CoREST Antibody

Binding Specificity: Middle Region

Purpose: RCOR1 Antibody - middle region

Sequence: DEVLQEWEAE HGKEETNGPS NQKPVKSPDN SIKMPEEEDE APVLDVRYAS

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against RCOR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RCOR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34346-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CoREST

Target: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Alternative Name: RCOR1

Background:

Background Information: RCOR1 is a functional corepressor required for regulation of neural-specific gene expression.The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: REST corepressor 1

Alternative Symbols: RCOR, COREST

Protein Name: REST corepressor 1

Molecular Weight: 53kDa

Gene ID: 23186

NCBI Accession: NP_055971

UniProt: Q9UKL0

Pathways: Regulation of Hormone Metabolic Process, Chromatin Binding