KCNJ3 antibody (C-Term)

Catalog No. ABIN2776140

The Rabbit Polyclonal anti-KCNJ3 antibody is suitable to detect KCNJ3 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog and Rabbit. It has been validated for WB.

Quick Overview for KCNJ3 antibody (C-Term) (ABIN2776140)

Target: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNJ3 Antibody

Binding Specificity: C-Term

Purpose: Kcnj3 Antibody - C-terminal region

Sequence: QEEMLLMSSP LIAPAITNSK ERHNSVECLD GLDDISTKLP SKLQKITGRE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Kcnj3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35081-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNJ3

Target: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Alternative Name: Kcnj3

Background:

Background Information: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Gene Name: Potassium inwardly-rectifying channel, subfamily J, member 3

Alternative Symbols: GIR, Kcnf, Kir3, GIRK1, Kcnf3, Kcnj1, GIRK-1, Kir3.1

Protein Name: G protein-activated inward rectifier potassium channel 1

Molecular Weight: 56kDa

Gene ID: 16519

NCBI Accession: NP_032452

UniProt: P63250