MLC1 antibody (Middle Region)

Catalog No. ABIN2776210

This Rabbit Polyclonal antibody specifically detects MLC1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Guinea Pig.

Quick Overview for MLC1 antibody (Middle Region) (ABIN2776210)

Target: MLC1

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MLC1 Antibody

Binding Specificity: Middle Region

Purpose: MLC1 Antibody - middle region

Sequence: SDSANILDEV PFPARVLKSY SVVEVIAGIS AVLGGIIALN VDDSVSGPHL

Predicted Reactivity: Cow: 91%, Dog: 86%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 83%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MLC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MLC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35249-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MLC1

Target: MLC1

Background:

Background Information: MLC1 may be a transporter. It may act as a non-selective neuronal cation channel.The function of this gene product is unknown, however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: Megalencephalic leukoencephalopathy with subcortical cysts 1

Alternative Symbols: VL, LVM, MLC

Protein Name: Membrane protein MLC1

Molecular Weight: 41kDa

Gene ID: 23209

NCBI Accession: NP_055981

UniProt: Q15049