Mucolipin 3 antibody (Middle Region)

Catalog No. ABIN2776223

This Rabbit Polyclonal antibody specifically detects Mucolipin 3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Horse, Cow and Zebrafish (Danio rerio).

Quick Overview for Mucolipin 3 antibody (Middle Region) (ABIN2776223)

Target: Mucolipin 3 (Mcoln3)

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mucolipin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Mucolipin 3 Antibody

Binding Specificity: Middle Region

Purpose: MCOLN3 Antibody - middle region

Sequence: TVELQFKLKA INLQTVRHQE LPDCYDFTLT ITFDNKAHSG RIKISLDNDI

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against MCOLN3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MCOLN3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35278-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Mucolipin 3

Target: Mucolipin 3 (Mcoln3)

Alternative Name: MCOLN3

Background:

Background Information: The specific function of this protein remains unknown.Mucolipins constitute a family of cation channel proteins with homologs in mouse, Drosophila, and C. elegans. Mutations in the human MCOLN1 gene (MIM 605248) cause mucolipodosis IV (MIM 262650).[supplied by OMIM].

Gene Name: Mucolipin 3

Alternative Symbols: TRPML3, TRP-ML3

Protein Name: Mucolipin-3

Molecular Weight: 64 kDa

Gene ID: 55283

NCBI Accession: NP_060768

UniProt: Q8TDD5

Pathways: Sensory Perception of Sound