FXYD7 antibody (N-Term)

Catalog No. ABIN2776249

Product Details anti-FXYD7 Antibody

Target: FXYD7 (FXYD Domain Containing Ion Transport Regulator 7 (FXYD7))

Binding Specificity: N-Term

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FXYD7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MATPTQTPTK APEEPDPFYY DYNTVQTVGM TLATILFLLG ILIVISKKVK

Predicted Reactivity: Cow: 77%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against FXYD7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 80 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FXYD7

Target: FXYD7 (FXYD Domain Containing Ion Transport Regulator 7 (FXYD7))

Alternative Name: FXYD7 (FXYD7 Products)

Synonyms: 1110035I01Rik antibody, FXYD domain containing ion transport regulator 7 antibody, FXYD domain-containing ion transport regulator 7 antibody, FXYD7 antibody, Fxyd7 antibody

Background: The specific function of this protein remains unknown.This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, FXYD7, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.].
Alias Symbols: FLJ25096
Protein Interaction Partner: APPBP2, UBC, SGTA, APOE, FXYD7, ATP1B1, ATP1A1,
Protein Size: 80

Molecular Weight: 8 kDa

Gene ID: 53822

NCBI Accession: NM_022006, NP_071289

UniProt: P58549