KCNV2 antibody (N-Term)

Catalog No. ABIN2776273

This Rabbit Polyclonal antibody specifically detects KCNV2 in WB. It exhibits reactivity toward Human and Pig.

Quick Overview for KCNV2 antibody (N-Term) (ABIN2776273)

Target: KCNV2 (Potassium Channel, Subfamily V, Member 2 (KCNV2))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNV2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNV2 Antibody

Binding Specificity: N-Term

Purpose: KCNV2 Antibody - N-terminal region

Sequence: RSGSQASIHG WTEGNYNYYI EEDEDGEEED QWKDDLAEED QQAGEVTTAK

Predicted Reactivity: Human: 100%, Pig: 79%

Characteristics: This is a rabbit polyclonal antibody against KCNV2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNV2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35396-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNV2

Target: KCNV2 (Potassium Channel, Subfamily V, Member 2 (KCNV2))

Alternative Name: KCNV2

Background:

Background Information: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. KCNV2 is strongly expressed in pancreas and has a weaker expression in several other tissues.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.

Gene Name: Potassium channel, subfamily V, member 2

Alternative Symbols: Kv8.2, RCD3B, KV11.1

Protein Name: Potassium voltage-gated channel subfamily V member 2

Molecular Weight: 62kDa

Gene ID: 169522

NCBI Accession: NP_598004

UniProt: Q8TDN2