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NMI antibody (Middle Region)

NMI Reactivity: Human, Rat, Mouse, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776425
  • Target See all NMI Antibodies
    NMI (N-Myc (And STAT) Interactor (NMI))
    Binding Specificity
    • 9
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 35
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Guinea Pig, Horse
    Host
    • 27
    • 8
    Rabbit
    Clonality
    • 29
    • 6
    Polyclonal
    Conjugate
    • 26
    • 3
    • 2
    • 2
    • 1
    • 1
    This NMI antibody is un-conjugated
    Application
    • 27
    • 15
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    SFSKSRNGGG EVDRVDYDRQ SGSAVITFVE IGVADKILKK KEYPLYINQT
    Predicted Reactivity
    Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against NMI. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human NMI
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    Discover our top product NMI Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 307 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NMI (N-Myc (And STAT) Interactor (NMI))
    Alternative Name
    NMI (NMI Products)
    Synonyms
    fj02e01 antibody, wu:fj02e01 antibody, NMI antibody, MGC108489 antibody, N-myc and STAT interactor antibody, N-myc (and STAT) interactor antibody, N-myc and STAT interactor L homeolog antibody, NMI antibody, Nmi antibody, nmi antibody, nmi.L antibody
    Background
    NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has high expression in myeloid leukemia cell lines. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: HSPA8, GCSH, GOLGA8EP, HDDC3, C9orf72, TXLNA, TXLNB, CNKSR3, LCA5L, C1orf216, SFR1, TUBA3E, MTMR9, COPS7B, BRMS1, KDM1A, POMZP3, HHLA3, EMILIN1, SNAPC5, MAD2L1BP, NMI, MTMR6, SCEL, TRAF5, UBC, PSMG3, OXR1, EXOSC4, TOLLIP, CYHR1, VPS26A, H1FX, NAA10, TBCD,
    Protein Size: 307
    Molecular Weight
    35 kDa
    Gene ID
    9111
    NCBI Accession
    NM_004688, NP_004679
    UniProt
    Q13287
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