APOBEC3F antibody (C-Term)

Catalog No. ABIN2776643

The Rabbit Polyclonal anti-APOBEC3F antibody is suitable to detect APOBEC3F in samples from Human and Pig. It has been validated for WB.

Quick Overview for APOBEC3F antibody (C-Term) (ABIN2776643)

Target: APOBEC3F (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3F (APOBEC3F))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBEC3F antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APOBEC3F Antibody

Binding Specificity: C-Term

Purpose: APOBEC3F Antibody - C-terminal region

Sequence: ASVEIMGYKD FKYCWENFVY NDDEPFKPWK GLKYNFLFLD SKLQEILE

Predicted Reactivity: Human: 100%, Pig: 100%

Characteristics: This is a rabbit polyclonal antibody against APOBEC3F. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human APOBEC3F

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41136-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for APOBEC3F

Target: APOBEC3F (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3F (APOBEC3F))

Alternative Name: APOBEC3F

Background:

Background Information: APOBEC3F is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F

Alternative Symbols: A3F, KA6, ARP8, BK150C2.4.MRNA

Protein Name: DNA dC->dU-editing enzyme APOBEC-3F

Molecular Weight: 45kDa

Gene ID: 200316

NCBI Accession: NP_660341

UniProt: Q8IUX4