WNT2B antibody (Middle Region)

Catalog No. ABIN2776710

There is 1 publication for this product available. The Rabbit Polyclonal anti-WNT2B antibody is suitable to detect WNT2B in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig and Horse. It has been validated for WB and IHC.

Quick Overview for WNT2B antibody (Middle Region) (ABIN2776710)

Target: WNT2B (Wingless-Type MMTV Integration Site Family, Member 2B (WNT2B))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-WNT2B Antibody

Binding Specificity: Middle Region

Sequence: LRTCWRALSD FRRTGDYLRR RYDGAVQVMA TQDGANFTAA RQGYRRATRT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against WNT2B. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WNT2B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-WNT2B antibody (ABIN2776710)

Chigita, Sugiura, Abe, Kobayashi, Shimoda, Onoda, Shirasuna: "CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of ?-catenin in carcinoma cells." in: International journal of oncology, Vol. 41, Issue 6, pp. 2021-8, (2012) (PubMed).

Target Details for WNT2B

Target: WNT2B (Wingless-Type MMTV Integration Site Family, Member 2B (WNT2B))

Alternative Name: WNT2B

Background: WNT2B is a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.
Alias Symbols: WNT13, XWNT2
Protein Interaction Partner: RAD21, BRCA1,
Protein Size: 372

Molecular Weight: 41 kDa

Gene ID: 7482

NCBI Accession: NM_004185, NP_004176

UniProt: Q5T6U1

Pathways: WNT Signaling