FZD4 antibody (C-Term)

Catalog No. ABIN2776714

This Rabbit Polyclonal antibody specifically detects FZD4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog, Rabbit and Zebrafish (Danio rerio).

Quick Overview for FZD4 antibody (C-Term) (ABIN2776714)

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Reactivity: Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FZD4 Antibody

Binding Specificity: C-Term

Purpose: FZD4 Antibody - C-terminal region

Sequence: LDALTGFVVA PLFTYLVIGT LFIAAGLVAL FKIRSNLQKD GTKTDKLERL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GPCR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human FZD4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41265-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FZD4

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Alternative Name: FZD4

Background:

Background Information: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

Gene Name: frizzled class receptor 4

Alternative Symbols: Fz4, EVR1, FEVR, Fz-4, FzE4, GPCR, hFz4, CD344, FZD4S

Protein Name: frizzled-4

Molecular Weight: 47kDa

Gene ID: 8322

NCBI Accession: NP_036325

UniProt: Q9ULV1

Pathways: WNT Signaling, Hormone Transport, Sensory Perception of Sound