MSH5 antibody (N-Term)

Catalog No. ABIN2776765

The Rabbit Polyclonal anti-MSH5 antibody has been validated for WB. It is suitable to detect MSH5 in samples from Human.

Quick Overview for MSH5 antibody (N-Term) (ABIN2776765)

Target: MSH5 (MutS Homolog 5 (MSH5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSH5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MSH5 Antibody

Binding Specificity: N-Term

Sequence: KQRLLSGNYS FIPDAMTATE KILFLSSIIP FDCLLTPPGD LRFTPIPLLI

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MSH5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MSH5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 851 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MSH5

Target: MSH5 (MutS Homolog 5 (MSH5))

Alternative Name: MSH5

Background: MSH5 is a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4.This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4. Alternative splicing results in four transcript variants encoding three different isoforms.
Alias Symbols: DKFZp434C1615, G7, MGC2939, MutSH5, NG23, MUTSH5
Protein Interaction Partner: MSH4, GPS2, UBC,
Protein Size: 851

Molecular Weight: 95 kDa

Gene ID: 4439

NCBI Accession: NM_025259, NP_079535

UniProt: Q9UMP2

Pathways: M Phase