CFHR4 antibody (N-Term)

Catalog No. ABIN2776771

This Rabbit Polyclonal antibody specifically detects CFHR4 in WB. It exhibits reactivity toward Human and Rat.

Quick Overview for CFHR4 antibody (N-Term) (ABIN2776771)

Target: CFHR4 (Complement Factor H-Related 4 (CFHR4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFHR4 Antibody

Binding Specificity: N-Term

Sequence: LWVSCANGQE VKPCDFPEIQ HGGLYYKSLR RLYFPAAAGQ SYSYYCDQNF

Predicted Reactivity: Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against FHR4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FHR4

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFHR4

Target: CFHR4 (Complement Factor H-Related 4 (CFHR4))

Alternative Name: FHR4

Background: This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.
Alias Symbols: CFHL4, FHR-4, FHR4
Protein Interaction Partner: CDC42, CFHR4, C3,
Protein Size: 578

Molecular Weight: 63 kDa

Gene ID: 10877

NCBI Accession: NM_006684, NP_006675

UniProt: Q5DVJ7