CFHR4 antibody (C-Term)

Catalog No. ABIN2790060

This Rabbit Polyclonal antibody specifically detects CFHR4 in WB. It exhibits reactivity toward Human.

Quick Overview for CFHR4 antibody (C-Term) (ABIN2790060)

Target: CFHR4 (Complement Factor H-Related 4 (CFHR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFHR4 Antibody

Binding Specificity: C-Term

Purpose: CFHR4 Antibody - C-terminal region

Sequence: SNGEWSEPPR CIHPCIITEE NMNKNNIQLK GKSDIKYYAK TGDTIEFMCK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CFHR4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65159-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFHR4

Target: CFHR4 (Complement Factor H-Related 4 (CFHR4))

Alternative Name: CFHR4

Background:

Background Information: This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.

Gene Name: Complement factor H-related 4

Alternative Symbols: FHR4, CFHL4, FHR-4

Protein Name: cDNA FLJ77201, highly similar to Homo sapiens complement factor H-related protein 4A (FHR4 gene) EMBL BAF85441.1

Molecular Weight: 63kDa

Gene ID: 10877

NCBI Accession: NP_001188480

UniProt: A8K9N7