Complement Factor H-Related 4 (CFHR4) (N-Term) antibody

Details for Product No. ABIN2776771
Antigen
Epitope
N-Term
1
1
1
Reactivity
Human, Rat (Rattus)
5
Host
Rabbit
3
2
Clonality
Polyclonal
Application
Western Blotting (WB)
5
2
Options
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human FHR4
Blocking Peptide Blocking peptide for this product available: ABIN2182577
Sequence LWVSCANGQE VKPCDFPEIQ HGGLYYKSLR RLYFPAAAGQ SYSYYCDQNF
Predicted Reactivity Human: 100%, Rat: 79%
Characteristics This is a rabbit polyclonal antibody against FHR4. It was validated on Western Blot.
Purification Affinity Purified
Antigen
Alternative Name FHR4 (CFHR4 Antibody Abstract)
Background This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.
Alias Symbols: CFHL4, FHR-4, FHR4
Protein Interaction Partner: CDC42, CFHR4, C3,
Protein Size: 578
Molecular Weight 63 kDa
Gene ID 10877
NCBI Accession NM_006684, NP_006675
UniProt Q5DVJ7
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Complement Factor H-Related 4 (CFHR4) (N-Term) antibody (ABIN2776771) Host: Rabbit Target Name: FHR4 Sample Type: 721_B Whole Cell lysates Antibody D...