Claudin 18 antibody (Middle Region)

Catalog No. ABIN2776807

The Rabbit Polyclonal anti-Claudin 18 antibody (ABIN2776807) specifically detects Claudin 18 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Pig samples.

Quick Overview for Claudin 18 antibody (Middle Region) (ABIN2776807)

Target: Claudin 18 (CLDN18)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 18 Antibody

Binding Specificity: Middle Region

Sequence: LVTNFWMSTA NMYTGMGGMV QTVQTRYTFG AALFVGWVAG GLTLIGGVMM

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CLDN18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLDN18

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 261 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Claudin 18

Target: Claudin 18 (CLDN18)

Alternative Name: CLDN18

Background: CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells.
Alias Symbols: SFTA5, SFTPJ
Protein Size: 261

Molecular Weight: 28 kDa

Gene ID: 51208

NCBI Accession: NM_001002026, NP_001002026

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C