AK4 antibody (Middle Region)

Catalog No. ABIN2776810

This Rabbit Polyclonal antibody specifically detects AK4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for AK4 antibody (Middle Region) (ABIN2776810)

Target: AK4 (Adenylate Kinase 4 (AK4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AK4 Antibody

Binding Specificity: Middle Region

Purpose: AK3L1 Antibody - middle region

Sequence: RWIHPPSGRV YNLDFNPPHV HGIDDVTGEP LVQQEDDKPE AVAARLRQYK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against AK3L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AK3L1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41433-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AK4

Target: AK4 (Adenylate Kinase 4 (AK4))

Alternative Name: AK3L1

Background:

Background Information: AK3L1 is a member of the adenylate kinase family of enzymes. The protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides.This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.

Gene Name: Adenylate kinase 4

Alternative Symbols: AK3, AK 4, AK3L1, AK3L2

Protein Name: Adenylate kinase isoenzyme 4, mitochondrial

Molecular Weight: 25kDa

Gene ID: 205

NCBI Accession: NP_001005353

UniProt: P27144

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process