LBP antibody (Middle Region)

Catalog No. ABIN2776868

The Rabbit Polyclonal anti-LBP antibody (ABIN2776868) specifically detects LBP in WB. The antibody is reactive with Human, Rat, Rabbit, Pig, Horse and Dog samples.

Quick Overview for LBP antibody (Middle Region) (ABIN2776868)

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Reactivity: Human, Rat, Rabbit, Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LBP Antibody

Binding Specificity: Middle Region

Sequence: LLGSESSGRP TVTASSCSSD IADVEVDMSG DLGWLLNLFH NQIESKFQKV

Predicted Reactivity: Dog: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against LBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 481 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LBP

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Alternative Name: LBP

Background: LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI
Alias Symbols: MGC22233, BPIFD2
Protein Interaction Partner: TSC22D4, PYCRL, TRA2A, PRDX4, SETD1A, CBFA2T2, BAG6, PSMA3, SMAD3, HSPB1, FTH1, C4BPA, BST1, CAMP, APOA1, RPS21, CD14, CFHR1, IRF6,
Protein Size: 481

Molecular Weight: 51 kDa

Gene ID: 3929

NCBI Accession: NM_004139, NP_004130

UniProt: P18428

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process