GSTM1 antibody (C-Term)

Catalog No. ABIN2776985

The Rabbit Polyclonal anti-GSTM1 antibody (ABIN2776985) specifically detects GSTM1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Rabbit and Pig samples.

Quick Overview for GSTM1 antibody (C-Term) (ABIN2776985)

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GSTM1 Antibody

Binding Specificity: C-Term

Purpose: GSTM1 Antibody - C-terminal region

Sequence: PEKLKLYSEF LGKRPWFAGN KGLEKISAYM KSSRFLPRPV FSKMAVWGNK

Predicted Reactivity: Cow: 86%, Dog: 79%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GSTM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GSTM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41770-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSTM1

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Alternative Name: GSTM1

Background:

Background Information: Cytosolic and membrane-bound forms of glutathione S-transferase are two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM1 a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.

Gene Name: Glutathione S-transferase mu 1

Alternative Symbols: MU, H-B, GST1, GTH4, GTM1, MU-1, GSTM1-1, GSTM1a-1a, GSTM1b-1b

Protein Name: Glutathione S-transferase Mu 1

Molecular Weight: 21kDa

Gene ID: 2944

NCBI Accession: NP_666533

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity